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Topical tacrolimus (Protopic®) and topical pimecrolimus (Elidel®) are two non-steroidal topical treatments for eczema. They are anti-inflammatory in nature, and helps to reduce inflammation on the skin in eczema. Tacrolimus is used on more severe inflammation and pimecrolimus is used on milder inflammation. They can be used in adults and children over 2 years of age. They are meant to be applied once or twice a day, until the inflammation calms down. They do not prevent new areas of inflammation
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