The crash near the Louisville Muhammad Ali International Airport marked the deadliest accident in UPS Airlines history.

The NTSB confirmed a UPS cargo plane's left engine separated during takeoff before a fatal Louisville airport crash that killed 12 people and injured 11 others Tuesday.

LOUISVILLE, Ky. (AP) — A UPS cargo plane’s left wing caught fire and an engine fell off just before it crashed and exploded after takeoff in Kentucky, a federal official said Wednesday, offering the first investigative details about a disaster that killed at least 11 people, including a child.

The death toll climbed to at least 12 on Wednesday, Nov. 5, and several people remained unaccounted for, said Louisville Mayor Craig Greenberg.

The grim task of finding victims from the firestorm that followed the crash of a UPS cargo plane in Louisville, Kentucky, has entered a third day.

The power had just gone off and the ground was shaking at Grade A Auto Parts when the owner received a hysterical video call from his chief financial officer.

Video of the deadly Louisville, Kentucky, crash showed flames on one of the plane's wings and a huge fireball erupting as the aircraft hit the ground.

At least 12 people were killed and several others injured after a UPS plane crashed shortly after taking off from the Louisville International Airport on Tuesday.