Cooper Flagg's health is the biggest storyline in the East Region as top-seeded Duke awaits the return of its freshman sensation. The Blue Devils beat North Carolina and Louisville in the ACC Tournament without the ACC Player of the Year,

Here's a look at the players to watch, potential Cinderella teams and matchup analysis for each region of the 2025 NCAA men's basketball tournament.

This figures to be the oddest NCAA Tournament in memory, and that doesn't have anything to do with the fiasco the selection committee launched when CBS Sports host Adam Zucker revealed early Sunday evening the North Carolina Tar Heels would be involved in March Madness as something other than spectators.

The last time a freshman was the Most Outstanding Player of the NCAA Tournament was 2015, when point guard Tyus Jones piloted Duke to its fifth national championship.

Duke legend Jay Bilas gave his thoughts about Cooper Flagg's impact on the Blue Devils, showcasing himself as one of the best recent stars.