The ratio of posterior wall thickness to the minimum voltage of QRS complexes in limb leads and several parameters derived from electrocardiography could independently predict ATTR-CM. The ratio of ...

Between 21.4% and 57.8% of patients from a real-world ATTR-CM cohort would have been eligible to take part in clinical trials testing disease-modifying therapies. Inclusion and exclusion criteria used ...

Awareness of the key symptoms of NF1 can help in early diagnosis. A young male patient was diagnosed with neurofibromatosis type 1 (NF1) after undergoing detailed clinical investigations, according to ...

Of the 33,829 blood donors analyzed, only 179 were D negative (0.53%). This finding complements existing studies on the relative rarity of this blood type in Asia. Among East and Southeast Asian ...

In terms of glucocorticoid remission, the rituximab cohort achieved better results (52.1%) compared with the intravenous cyclophosphamide group (30.9%). Rituximab was found to be significantly ...

The levels of NT-proBNP, left ventricular mass index, maximal wall thickness, and E/E′ ratio were higher in patients with worse neurological stages compared to those in the early neurological stages ...

Emerging therapies such as bezuclastinib and elenestinib show promise in improving disease control with potentially fewer toxicities. Other novel strategies, such as immune-based therapies, are under ...

Only 1 participant experienced graft failure, which typically occurs at much higher frequencies in HCT for MF. The use of ruxolitinib with allogeneic hematopoietic cell transplantation (HCT) ...

CLL-related immune dysfunction, along with therapy-associated immunosuppression, contributes to impaired tumor surveillance. Patients with chronic lymphocytic leukemia (CLL) are at increased risk for ...

Microscopic examination of the patient's fibroblasts after treatment revealed improved FXN levels. Antisense oligonucleotide (ASO) therapy appears to be a viable therapeutic alternative for Friedreich ...

Immunohistochemistry can identify concomitant SM in acute myeloid leukemia, leading to better risk stratification and management. The most common forms of AML in pediatric patients are those ...

Whole-genome resequencing used to assess ATP7B genotypes found a higher frequency of impaired finger tapping in patients carrying the p.P992L mutation. A variety of sociodemographic factors were found ...