The news around wide receiver Brandon Aiyuk’s season-ending knee injury during the San Francisco 49ers’ 28-18 loss to the ...

It has been a nightmare season for Deebo Samuel and the San Francisco 49ers. Injuries have piled up and the team is off to a ...

San Francisco 49ers star receiver Brandon Aiyuk will miss the rest of the season after tearing ligaments in his right knee.

At an up-and-down 3-4, the reigning NFC champion San Francisco 49ers can't be reliably counted on as a bona fide contender.

WHERE: Raymond James Stadium (Tampa, Fla.) WHERE: State Farm Stadium (Glendale, Ariz.) ...

And yet Kyle Shanahan treated it like he treats all games: He played not to lose. So the 49ers lost.

Joe Jon Finley is now OU football's play caller. Finley, who has served as co-offensive coordinator and tight ends coach this ...

The Dallas Cowboys and San Francisco 49ers play on Sunday, Oct. 27 at Levi's Stadium in a game on the NFL Week 8 schedule.

The NFL free agent was spotted at the highly anticipated concert despite Kelce skipping the show due to his Kansas City Chiefs game schedule.

Malik Mustapha revealed his thoughts on the Patrick Mahomes "truck stick" moment that everybody is talking about.

The San Francisco 49ers had their worst fears confirmed on Monday. Per Jordan Schultz of Fox Sports, tests determined that ...

Kansas City Chiefs quarterback Patrick Mahomes says matchups against teams of the San Francisco 49ers' caliber prepare the ...