The San Francisco 49ers’ practice schedule began a day later than normal with a Monday night showdown against the Detroit Lions coming up in Week 17. Their practice report opened with some good news on the injury front.

When will Isaac Guerendo return and play? Will Isaac Guerendo be back again this season? Read the latest Isaac Guerendo injury updates and return date for Week 17 (2024).

RB Jordan Mason filled in admirably to start the year, but he was hit with a shoulder injury in Week 6 that he battled until McCaffrey’s return in Week 10. McCaffrey and Mason were both hurt in a Week 13 loss to the Buffalo Bills, which pushed rookie fourth-round pick RB Isaac Guerendo into the starting role.

The San Francisco 49ers are making a final push to close out a lost season on a strong note. Injuries have decimated the reigning NFC champs. Isaac Guerendo, however, provided a promising update. The alternate running back appears to be on his way back,