Following the significant losses of players due to injury and illness, including Brandon Aiyuk, San Francisco 49ers head ...

And yet Kyle Shanahan treated it like he treats all games: He played not to lose. So the 49ers lost.

Kyle Shanahan detailed the conversation he had with quarterback Brock Purdy in the 49ers' locker room after San Francisco's ...

The news around wide receiver Brandon Aiyuk's season-ending knee injury during the San Francisco 49ers' 28-18 loss to the ...

Kyle did something strange after the 49ers lost 28-18 to the Chiefs on Sunday. After his postgame press conference, he walked ...

Finally, it appears that the 49ers have some received some good news from an injury standpoint. On Monday, a day after his ...

The San Francisco 49ers fell to the Kansas City Chiefs 28-18 at Levi's® Stadium in Week 7. Here's what both teams had to say ...

San Francisco 49ers head coach Kyle Shanahan spoke with reporters during a conference call on Monday, the day after the ...

San Francisco 49ers head coach reveals Deebo Samuel is dealing with a tough condition. Kyle Shanahan says there's no timeline ...

This week's 49ers mailbag is stocked with questions (and answers) regarding their offensive shortcomings, fourth-quarter ...

The first year of Aiyuk's $120 million four-year contract extension, which was marked by a long dispute with the 49ers, ...