Demyelination is damage to the myelin sheath around nerves. ... In unmyelinated neurons, a signal can travel along the nerves at about 0.5 to 10 meters per second, ...

Mitochondrial abnormalities, or problems in cells' powerhouses, contribute to nerve cell death linked to motor control in MS, ...

Importantly, the loss of axons and their neurons is a major factor determining long-term disability in patients, although the primary cause of the disease is demyelination.

UC Riverside study may lead to new treatments for multiple sclerosis. Multiple sclerosis (MS) affects an estimated 2.3 ...

More information: Greg J. Duncan et al, Remyelination protects neurons from DLK-mediated neurodegeneration, Nature Communications (2024). DOI: 10.1038/s41467-024-53429-5 Provided by Oregon Health ...

Through their pattern of firing, neurons influence the behavior of the cells that upon maturation will provide insulation of neuronal axons, according to a new study publishing 22 August in the ...

Without effective repair, neurons become more susceptible to degeneration, worsening symptoms over time. Demyelination affects both white and gray matter in the brain.

The disabling effects of multiple sclerosis may be caused in part by damaged connections between neurons, and this can be seen in the eye, UC San Francisco researchers have found. They showed that ...

Multiple sclerosis (MS) affects an estimated 2.3 million people worldwide. Approximately 80% of people with MS have inflammation in the cerebellum, the part of the brain that helps control movement ...

The neurons of the brain are protected by an insulating layer called myelin. ... Thus, investigational therapies that boost C1QL1 may hold promise against demyelinating diseases.

These problems—less energy, loss of myelin, and damaged neurons—start early, but the actual death of the brain cells tends to happen later, as the disease becomes more severe.