ARIA with edema or effusions (ARIA-E) occurred in 24.4% of donanemab-treated patients in the placebo-controlled trials and 19.8% of donanemab-treated patients in the open-label extension.

These inhibitory neurons play a major role in our perception. The brain has evolved this precise wiring and division of labor among different neuron types to act as the brakes in the visual system ...

Whether mice persist with a task, explore new options or give up comes down to the activity of three types of neuron in the brain. In experiments, researchers at University College London (UCL ...

in T1-weighted images (T1WIs) and the corresponding apparent diffusion coefficient (ADC) value and further explored the altered polarization patterns of AQP4 in various affected edema regions in ...

Stroke is the leading cause of global mortality and disability. Cerebral edema and intracranial hypertension are common complications of cerebral infarction and the major causes of mortality. The ...

Vascular endothelial cells (vECs) in the brain exhibit structural and functional heterogeneity. Fenestrated, permeable brain vasculature mediates neuroendocrine function, body-fluid regulation, and ...