Deebo Samuel revealed why San Francisco quarterback Brock Purdy was upset after Sunday's win over the Tampa Bay Buccaneers.

Christian McCaffrey returned to San Francisco 49ers practice on Wednesday with a clean bill of health after making his season ...

Kittle injured his hamstring during the 49ers’ Week 10 win over the Tampa Bay Buccaneers. Shanahan told reporters in a press ...

Star pass-catcher George Kittle and the San Francisco 49ers face the Seattle Seahawks on Sunday at 4:05 p.m. ET, at Levi’s ...

A handful of players were absent from the first Week 11 practice for the 49ers with four of them being star players.

The San Francisco 49ers earned a hard-fought victory on Sunday against the Tampa Bay Buccaneers, securing back-to-back wins ...

Here are your top 49ers storylines for Wednesday, November 13th.

Listen in as players from the 49ers locker room shared their excitement for DB Deommodore Lenoir's five-year contract ...

The San Francisco 49ers are preparing for their Week 11 contest against the Seattle Seahawks on Sunday at Levi's Stadium in ...

Former Super Bowl-winning coach Jon Gruden is looking to jump back into the NFL coaching fray, according to Boomer Esiason.

The San Francisco 49ers overcame a late-game surge by the Tampa Bay Buccaneers to win 23-20 in Week 10. All-Pro running back ...