Intravenous thrombolysis remains a standard treatment for acute ischemic stroke within 4.5 hours after onset. Vascular ...

Corporatization” of health care, a process predicted decades ago, now refers to the general trend throughout the industry toward higher levels of integrated control by consolidated profit-seeking ...

A 63-year-old woman was evaluated for dyspnea and edema. Soft-tissue thickening was noted in the retroperitoneum and mediastinum and around the heart and vessels. A diagnosis was made.

Musunuru and colleagues 1 describe in the Journal an innovative approach in which gene editing is applied in the treatment of a very rare disease, the severe urea-cycle disorder carbamoyl ...

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Explore a collection of articles and other resources on the Coronavirus (Covid-19) outbreak, including clinical reports, management guidelines, and commentary.

Atrial fibrillation affects more than 33 million people worldwide and is a leading cause of stroke. 1 Alcohol consumption is ingrained in Western culture, with 57% of American adults drinking ...

The authors review the pathophysiology, revised diagnostic definitions, and management of acute kidney injury, a common condition in patients with cirrhosis.

Hereditary angioedema is a rare, potentially life-threatening disorder characterized by attacks of cutaneous and submucosal swelling. Quincke first described its clinical presentation, and Osler ...

Autoimmune pulmonary alveolar proteinosis (aPAP) is a disease characterized by alveolar filling that leads to progressive accumulation of surfactant in alveoli, hypoxemia, and in some patients ...

Without effective treatment, pulmonary arterial hypertension results in high morbidity and mortality. This review discusses the pathogenesis of the disorder, the thorough clinical evaluation requir ...