Objective To retrospectively investigate safety and efficacy of nusinersen in a large cohort of adult Italian patients with spinal muscular atrophy (SMA). Methods Inclusion criteria were: (1) clinical ...
The opioid crisis is a significant public health issue that has led to a rising number of overdose deaths over the past 25 years. Cue-induced drug craving leads to a high risk of relapse, which urged ...
Background: There are no studies of autonomic function comparing Alzheimer’s disease (AD), vascular dementia (VAD), dementia with Lewy bodies (DLB) and Parkinson’s disease dementia (PDD). Aims: To ...
A method was developed for making EMG recordings from the four individual muscles of the anterior abdominal wall. It was then demonstrated that these muscles have different and distinguishable actions ...
Background Staging of disease severity is useful for prognosis, decision-making and resource planning. However, no commonly used, validated staging system exists for amyotrophic lateral sclerosis (ALS ...
Objectives: To determine the prevalence of dementia in people under the age of 65 in a large catchment area, and use these figures to estimate the number of younger people affected by dementia in the ...
Background Lesion resolution is often observed in children with myelin-oligodendrocyte glycoprotein antibody-associated disease (MOGAD), and asymptomatic lesions are less commonly reported in MOGAD ...
Correspondence to Hanneke Frederica Maria Rhodius-Meester, Alzheimer Center, VU University Medical Center, Amsterdam 1007 MB, The Netherlands; h.rhodius{at}vumc.nl Patients with dementia have a ...
Dr Massimo Zeviani, Division of Biochemistry and Genetics, Istituto Nazionale Neurologico “Carlo Besta”, Via Celoria 11, Milano 20133, Italy. AIM To contribute to the establishment of a rational ...
BACKGROUND Tic disorders presenting during adulthood have infrequently been described in the medical literature. Most reports depict adult onset secondary tic disorders caused by trauma, encephalitis, ...
Correspondence to Dr Zhang-Yu Zou, Department of Neurology, Fujian Medical University Union Hospital, No. 29, Xinquan Road, Gulou District, Fuzhou, 350001, Fujian, China; pumczzy{at}gmail.com or ...
Poststroke fatigue is a debilitating symptom and is poorly understood. Here we summarise molecular, behavioural and neurophysiological changes related to poststroke fatigue and put forward potential ...