Carbonyl‐olefin metathesis reactions have emerged as an invaluable strategy for the direct formation of carbon–carbon bonds, enabling the efficient construction of complex molecular architectures.

In separate studies, researchers in Canada and the U.S. have demonstrated procedures for carrying out olefin metathesis reactions on the surface of metals (Science 2005, 309, 588 and 591).

When it comes to assembling macrocyclic olefins, few reactions can compete with the ease and efficiency of ring-closing metathesis. But the reaction has a downside: It suffers from poor ...

The olefin metathesis reaction produces new carbon-carbon double bonds by swapping the carbon atoms in olefins. The catalyst facilitates this swapping by breaking the original double bonds and ...

Two decades after the “development of the metathesis method in organic synthesis” was honored with a Nobel Prize, this chemical transformation is in full swing across many industrial applications.

(Phys.org)—Olefin metathesis reactions where two allyls switch substituent groups, has proved to be a useful carbon-carbon bond forming reaction for drug discovery and other industrial processes.

Catalytic Z-selective olefin cross-metathesis for natural product synthesis. Nature, 2011; 471 (7339): 461 DOI: 10.1038/nature09957 ...

Figure 2: Ring-closing metathesis (RCM) and cross-metathesis (CM) in the synthesis of Eisais pladienolide drug candidate. Researchers from Boston College and the Massachusetts Institute of Technology ...

“The olefin metathesis reaction is among the most widely applicable catalytic reactions for carbon-carbon double bond formation,” explained Satoshi Takebayashi, a researcher at the Okinawa ...

Olefin metathesis is a reversible reaction and you always run the risk of going back and forth between product and starting material, which forces you to end up with a lower energy and less ...