Introduction Preterm-born infants are particularly vulnerable to poor air quality, which may contribute to respiratory ...

Elexacaftor-tezacaftor-ivacaftor (ETI) has transformed cystic fibrosis (CF) care for over 90% of people with CF (pwCF) in countries with access to treatment.1 Clinical trial and ‘real-world’ reports ...

Introduction Development of novel treatments for cough and its management are hampered by the lack of well validated objective cough frequency methodologies. Previous validations have been performed ...

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Low-dose CT screening reduces lung cancer mortality,1 2 and the policy debate has moved beyond whether screening works to how programmes should be designed. Risk-based eligibility is central to that ...

PM 2.5, O 3 and survival gains from China’s clean air actions among patients with lung cancer: a 20-year registry-based cohort study in Beijing ...

Background Fibrotic hypersensitivity pneumonitis (FHP) is an irreversible lung disease with high morbidity and mortality. We sought to evaluate the safety and effect of pirfenidone on disease ...

Background: Caffeine is known to inhibit phosphodiesterases, to mobilise intracellular calcium, and to act as an antagonist at adenosine receptors, all of which can potentially alter nitric oxide (NO) ...

Background Non-dipping of nocturnal blood pressure (BP) is associated with target organ damage and cardiovascular disease. Obstructive sleep apnoea (OSA) is associated with incident non-dipping.

Background Obstructive sleep apnoea (OSA) is a heterogeneous disorder, and improved understanding of physiologic phenotypes and their clinical implications is needed. We aimed to determine whether ...

1 Department of Immunology and Microbiology, Laboratory of Clinical Immunology, KU Leuven, Leuven, Belgium 2 Department of Clinical and Experimental Medicine, Laboratory of Pneumology, KU Leuven, ...

Rationale Ventilator-associated pneumonia (VAP) is the most common nosocomial infections in patients admitted to the ICU. The adapted island model predicts several changes in the respiratory ...