The 49ers lost running back Raheem Mostert for the rest of the season to a knee injury and that means the backfield will have a different makeup this weekend than it did in Week One. It will include ...

SANTA CLARA, Calif. -- The San Francisco 49ers don't have a clear picture as to who will play running back for them Sunday night, but the pieces started to come together on Friday. While coach Kyle ...

Here's a head scratcher. The 49ers just selected their second running back of the draft. First, they traded up for Ohio State running back Trey Sermon in Round 3. Now, they've taken Louisiana running ...

Let's be honest. The 49ers drafting a running back in Round 3 this year was not a good sign for Trey Sermon. Sermon was the 49ers third-round pick last year -- they even traded up to get him. But he ...