Alcohol use disorders occur frequently in clinical practice, and US Food and Drug Administration (FDA)-approved pharmacotherapies (eg, disulfiram, naltrexone, acamprosate) are only moderately ...

Another possible risk factor for the development of topiramate-related cognitive side effects may be genetic predisposition. In the current paper, Cirulli and colleagues administered 100 mg of ...

The antiepileptic drug topiramate has been FDA-approved for migraine prevention. This agent might also be useful in treating patients in whom migraine has become chronic. A total of 46 US centers ...

A new study suggests that using topiramate in early pregnancy, particularly at the high doses used for epilepsy, increases the risk of oral clefts. The anti-epileptic drug topiramate has been ...

What is topiramate used for? Topiramate is commonly used in people with epilepsy to treat and prevent seizures, sometimes called convulsions. Topiramate is commonly used in people to help prevent a ...

Credit: Shutterstock. The HER-MES trial included 777 adults with episodic or chronic migraine (at least 4 migraine days/month) who were treatment-naïve, not suitable for, or had previously failed up ...

Heavy alcohol consumption is common in the United States and takes a personal and societal toll, with an annual estimated cost of $223.5 billion. Researchers have shown that the anticonvulsant ...

Findings showed 12.1% of atogepant-treated patients discontinued treatment due to adverse events compared with 29.6% of topiramate-treated patients. Topline results were announced from a phase 3 trial ...

Avoid drinking alcohol while taking Topiramate as it can cause side effects like drowsiness, dizziness, an increased risk of seizures, unusual behavior and mental health problems like suicidal ...

The anticonvulsant topiramate causes dose-dependent weight loss in humans and in animal models of diabetes. Toplak and colleagues, therefore, investigated the efficacy and safety of topiramate as an ...

Topiramate (Topamax) 25 mg once daily, titrated to 300 mg/day in two divided doses for 14 weeks, was evaluated in a placebo-controlled randomized trial in 371 patients aged 18-65 years with alcohol ...

Review the side-effects of Topiramate as documented in medical literature. The term "side effects" refers to unintended effects that can occur as a result of taking the medication. In majority of the ...