Please provide your email address to receive an email when new articles are posted on . Both excessive and long-term alcohol consumption, as well as any spirit consumption, predict the development of ...

The presence of tophi - crystal deposits of uric acid found on the surface of the joints or in the skin and cartilage - in people with gout can increase their risk of developing cardiovascular disease ...

Pegloticase quickly resolved tophi among patients with gout who responded to the treatment, according to data published in Arthritis Research & Therapy. “Pegloticase is a recombinant mammalian uricase ...

This study demonstrates that gout patients from the US and three EU countries suffer from significantly decreased HRQOL, with the average patient suffering decreased mental as well as physical ...

The advanced imaging method dual-energy CT (DECT) has been found to be a reliable measure of tophus size and composition in patients with gout, according to new research published in Journal of ...

— REDUCE 1 is a study running in parallel with REDUCE 2 to evaluate pozdeutinurad's efficacy in lowering serum urate (sUA) levels and resolution of target tophi in gout patients — SAN DIEGO, July 1, ...

Krystexxa, a PEGylated uric acid specific enzyme, is approved for the treatment of refractory chronic gout. One study retrospectively analyzed data from two 6-month, randomized clinical trials that ...

A small exploratory study from Dalbeth et al. investigating the effect of pegloticase on radiographic damage in patients with tophaceous gout has shown that this treatment results in profound urate ...

Bone erosion in patients with gout and tophi was associated with tophi duration, drinking history, ulceration, and serum creatinine levels. Bone erosion in patients with gout and tophi was associated ...

The characteristics of the sample are presented in Table 1 and Table 2. The average age was 60.9 years, and patients had been diagnosed an average of 12 years. Most were male (81%), and 38% were ...