Stimulating the liver to generate signals normally produced by the thymus can reverse age-related declines in T-cell populations.

As people age, their immune system function declines. T cell populations become smaller and can't react to pathogens as quickly, making people more susceptible to a variety of infections. To try to ...

Northwestern Medicine scientists have identified the cellular mechanisms that cause immune cells to differentiate and ...

Scientists uncover a new “recipe” that shows how exhausted T cells can be reprogrammed to regain their ability to attack tumors.

The Golgi apparatus modifies, sorts and packages proteins to be sent to their final destinations, whether that's within or outside of the cell. It's a core function, but little studied in the setting ...

The Golgi apparatus modifies, sorts and packages proteins to be sent to their final destinations, whether that's within or outside of the cell. It's a core function, but little studied in the setting ...

Scientists discovered key genetic factors that determine whether a T cell acts as a powerful disease fighter or enters an ineffective, exhausted state. Turning off two transcription factors allowed ...

In 2024, Professor Sebastian Kobold's research group at LMU University Hospital had already shown that the metabolite ...

CD8 + cytotoxic T lymphocytes (CTLs) serve as central effectors in cancer immunotherapy by directly eliminating tumor cells. However, current clinical therapies face significant limitations. These ...

A new study identifies an extreme but effective way that brain immune cells can prevent the parasite Toxoplasma gondii from spreading: they kill themselves to eliminate the dangerous microbes they ...