International mpox trial finds no clinical benefit from tecovirimat

An international, randomized, double-blind, placebo-controlled Phase III study—the largest of its kind for mpox—found that tecovirimat did not improve clinical outcomes for adults with clade II mpox ...
ascopubs.org

Randomized Placebo-Controlled Trial of Topical Capsaicin for Delayed Chemotherapy-Induced Nausea and Vomiting

International Survey of Psychosocial Care for Cancer Survivors in Low-/Middle- and High-Income Countries: Current Practices, Barriers, and Facilitators to Care Patients receiving capsaicin had a ...
ascopubs.org

Randomized double-blind placebo-controlled trial evaluating pregabalin for chronic cough in patients with lung cancer.

Preventive effect of naldemedine for opioid-induced constipation in patients with cancer starting opioids: A multicenter, double-blinded, randomized, placebo-controlled, phase 3 trial. This is an ASCO ...
The New England Journal of Medicine

A Placebo-Controlled Trial of Percutaneous Coronary Intervention for Stable Angina

Percutaneous coronary intervention (PCI) is frequently performed to reduce the symptoms of stable angina. Whether PCI relieves angina more than a placebo procedure in patients who are not receiving ...