Acute hepatic porphyria (AHP) is one of a group of disorders that are triggered by a buildup of pigments called porphyrins in your liver and elsewhere. The disorder can cause nerve problems and other ...

This page lists all known medications that could potentially lead to 'Variegate porphyria' as a side effect. It's important to note that mild side effects are quite common with medications. The ...

Porphyrias fall into two main categories based on their symptoms: acute forms cause severe abdominal pain and neurological symptoms during episodes, while cutaneous forms primarily cause skin ...

Patients with symptomatic acute hepatic porphyria were found to be at greater risk of accessing long-term sick leave and disability pension compared with the general population, but were not shown to ...

Use of the RNA inhibitor givosiran was shown to reduce expression of delta-aminolevulinic acid synthase 1, in turn reducing the severity of acute attacks and chronic symptoms for patients with severe ...

Variegate porphyria (VP) is an autosomal dominant condition that results from the deficiency of protoporphyrinogen oxidase (PPOX, EC 1.3). The build-up of porphyrin precursors delta-aminolevulinic ...

Acute porphyria is a group of uncommon diseases that can cause severe, potentially life-threatening attacks of abdominal pain, nausea, vomiting and paralysis. Liver transplantation is currently the ...

A common factor in all types of porphyria is an increase in the rate limiting enzyme five aminolaevulinic (ALA) synthesis which initiates the haem biosynthesis. Porphyria is commonly classified ...

BETHESDA, Md., May 17, 2024 /PRNewswire/ -- United Porphyrias Association (UPA) is proud to announce May 18 as Global Porphyria Day. Global Porphyria Day is intended to create awareness that prompts ...