Dental pulp injury caused by trauma or deep caries often leads to inflammation, tissue necrosis, and eventual loss of tooth vitality. In severe cases, bacterial invasion and sustained immune responses ...

Researchers at the University of São Paulo in Brazil have discovered connections in the mechanisms involved in dental pulp inflammation and root apex damage. The findings may lead to medications that ...

The key element in the mechanisms in question is tumor necrosis factor-α receptor-1, TNFR1, which becomes pro-inflammatory on binding to the cytokine TNF-α. In one of the situations analyzed, the ...

Dental pulp regeneration remains a major clinical challenge. Researchers have discovered that SMAD7 directly forms a ...

When a patient is rushed in with an injured tooth, what is the best approach to preserve the tooth's pulp, pulpal space, and root? DrBicuspid.com spoke with four endodontists on best practices in ...