A new technology allows scientists to map, in single cells, the DNA binding sites of transcription factors and other regulatory proteins that control gene activity, according to a study led by ...

D&D‑seq uses base editing to record DNA–protein interactions in single cells, enabling multiomics mapping of transcription factor and other regulatory proteins.

Protein-Protein Interactions (PPIs) are critical for biological systems to function properly. Strong interactions maintain structural integrity and function, whereas weaker interactions enable ...

Researchers from the MRC Protein Phosphorylation and Ubiquitylation Unit at the University of Dundee, together with collaborators from ETH Zürich, the Malopolska Center of Biotechnology and the ...

Researchers capture first-of-its-kind video of dynein–Lis1 protein interaction, supporting future drug development for neurological disorders. Our cells rely on microscopic highways and specialized ...

A research team at Florida State University's Institute of Molecular Biophysics and Department of Chemistry and Biochemistry has discovered how a protein found in the human body interacts with RNA in ...

By combining CRISPR knock-in with small peptide tags, researchers can study proteins in their native cellular context, ...

A new method screens large libraries of synthetic cyclic peptides to identify compounds that can enter cells for therapeutic effect.

Textbooks often depict proteins in one conformation, but real life, as usual, is much messier. While some proteins have stable, unchanging structures, many others have intrinsically disordered regions ...

Membrane proteins and membrane lipids are essential partners in various biological processes, and elucidating their structures in a natural membrane environment is crucial for enhancing our ...