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How certain proteins affect vascular and pancreatic health
Protein intake influences far more than muscle mass; it shapes vascular function and pancreatic insulin dynamics over time.
Inspired by the simple mechanism of a seesaw—when one side goes up, the other side goes down—researchers asked an intriguing ...
In the same way that multiple snapshots of a galloping horse provide information about how the horse moves, multiple snapshots of a protein changing shape can improve scientific understanding of that ...
Understanding the structure of proteins is critical for demystifying their functions and developing drugs that target them. To that end, a team of researchers at Brown University has developed a way ...
The Golgi apparatus is a central organelle in eukaryotic cells, instrumental in processing, modifying and sorting proteins and lipids. Its dynamic architecture features discrete cisternae organised ...
Protein-Protein Interactions (PPIs) are critical for biological systems to function properly. Strong interactions maintain structural integrity and function, whereas weaker interactions enable ...
Proteins are the molecular machines of cells. They are produced in protein factories called ribosomes based on their blueprint—the genetic information. Here, the basic building blocks of proteins, ...
Researchers at Kanazawa University report in eLife on deciphering the actin structure-dependent preferential cooperative binding of cofilin. The actin filament is a double-stranded helical structure ...
A novel protein cage system can control and visualize orientational changes in aromatic side chains upon ligand binding. By inducing coordinated molecular changes, this approach enables precise ...
Age-related changes in protein tagging and degradation may help explain how the brain declines over time and why diet can still influence these processes.
Observing proteins with precision in living cells has been a challenge for researchers across various disciplines. Now, Stefan Kubicek, PhD, and his team at CEMM Research Center for Molecular Medicine ...
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