Patrick Dempsey is keeping it real. The actor, 58, opens up in this week's issue of PEOPLE about being named Sexiest Man ...

Former Grey's Anatomy star Patrick Dempsey opened up about ageing and his self confidence a year after being named Sexiest ...

"We need to be able to talk about this openly without any shame," says the actor, whose mom died of cancer in 2014 ...

Patrick Dempsey is an actor best known for portraying neurosurgeon Derek Shepherd in multiple seasons of the ABC medical ...

Ellen Pompeo's character had a number of steamy scenes in Grey's Anatomy - something her husband, Chris Ivery, has spoken ...

While Patrick Dempsey's Derek Shepherd was killed and Ellen Pompeo's Meredith ... passion projects both within and outside of ...

Actor Patrick Dempsey called on the National Institutes of Health (NIH) to offer better holistic care for cancer patients ...

Patrick Dempsey has teased his involvement in Scream 7, the series' upcoming instalment, potentially reprising his role in ...

With Scream 7 moving forward without the Carpenter sisters, speculation suggests that the franchise may be shifting its focus ...

'Can't Buy Me Love' Star Amanda Peterson Died Of Drug Overdose, Authorities Say –– Morphine Use Triggered Her Tragic Death At 43 Amanda Peterson, best known for co-starring with Patrick ...

Patrick Dempsey says his eyes were opened when his mom was diagnosed with cancer. In an exclusive conversation with PEOPLE, the actor, 58, speaks candidly about his mom Amanda Dempsey's cancer ...

Actor Patrick Dempsey called on the National Institutes of Health (NIH) to offer better holistic care for cancer patients while receiving one of the 2024 George H.W. Bush Points of Light Awards on ...