Researchers identify PV neurons in the prefrontal cortex as the gatekeepers of drug addiction relapse, offering a new target for precision treatment.

Alzheimer's disease and schizophrenia are some of the most common brain disorders and have been associated with problems in cells that contain a type of protein, called parvalbumin. These ...

Parvalbumin (PV) interneurons act as the brain’s rhythm keepers. By regulating local circuit activity and maintaining excitation–inhibition balance, they help stabilize cortical network function. When ...

Drug addiction carries an extremely high risk of relapse, as cravings can be reignited by minor stimuli even long after one has stopped using. Previously, this phenomenon was attributed to a decline ...

Researchers at Lund University in Sweden have created a method that makes it possible to transform the brain’s support cells into parvalbumin-positive cells. These cells act as the brain’s ...

Parvalbumin cells play a central role in keeping brain activity in equilibrium. They control nervcell signalling, reduce overactivity and make sure that the brain is working to a rhythm. Researchers ...

Researchers have found that dysfunction in an important cell subtype in the brain's neuronal network contribute to chronic symptoms in the neurodevelopmental disorder Dravet syndrome. Researchers from ...

A new study has discovered what researchers say is the first drug to fully reproduce the effects of physical stroke rehabilitation in model mice, following from human studies. A new study by UCLA ...

Neurons are the cells in the brain responsible for sending messages to the rest of the body, and scientists have long thought that they are settled into one subtype once they develop from stem cells, ...