Recovery from opioid use disorder (OUD) and maintenance of abstinence from opioid use is hampered by perseverant drug cravings that may persist for months after cessation of drug use. Drug cravings ...
A major obstacle in oxycodone addiction treatment is relapse during abstinence. In rats, oxycodone seeking intensifies during abstinence, and orbitofrontal cortex (OFC) is critical for this incubation ...