The orbitofrontal cortex (OFC), a subsection of the brain's frontal lobe, is known to play a part in value-based decision-making, the process of mentally weighing the outcome of different decisions ...

Life can be tricky. We have so many decisions to make. It's a good thing we have an orbitofrontal cortex and hippocampus to help us. These areas of the brain work together to help us sort through ...

New research published in JCCP Advances indicates that experiencing negative life events (NLE) during childhood is linked with a higher risk of developing symptoms of depression during young adulthood ...

In a recent study published in the journal JCPP Advances, a group of researchers investigated whether early negative life events (NLEs) predict depressive symptoms in young adulthood through ...

Newly identified brain cells evolved along the theme, "Life is uncertain; Eat dessert first." The neurons, located in the front part of the brain, are most active when the outcome of a decision is ...

The human brain is remarkably adept at adjusting what we hear based on contexts, like our current environment or priorities, but it's still unknown how exactly the brain helps us detect, filter and ...

Depression imposes a major global socioeconomic burden, and current pharmacotherapies face several limitations, including slow efficacy, adverse effects, and non-response rates of up to 55%, ...

Humans and other animals gradually learn what sounds or other sensory cues in their surroundings are meaningful or potentially threatening. Via a process known as habituation, they gradually learn to ...

Long-term brain recordings from four patients with chronic pain have led investigators at the University of California at San Francisco to identify brain signals that could serve as biomarkers for ...

The same areas of the brain-the medial orbitofrontal cortex-are engaged when people receive a reward or avoid a negative outcome. Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy ...