New treatments for cardiac hypertrophy, a thickening of the heart in response to pressure overload, could potentially treat or even reverse the condition after a new breakthrough discovery identified ...

Scientists have uncovered a mechanism behind the thickening of the heart muscle wall—a process tied to higher risk of irregular heart rhythms and heart failure. The findings—led by researchers at the ...

In a groundbreaking study, the regulatory role of the long noncoding RNA (lncRNA) Gm20257 in pathological cardiac hypertrophy has been elucidated, offering new insights into potential therapeutic ...

When the workload on the heart increases, the ventricular wall may thicken too, known as cardiac hypertrophy. This is an adaptive response that reduces pressure on the heart and maintains the activity ...

Researchers at the Centre for Genomic Regulation (CRG) in Barcelona have discovered a mechanism involving ribosomes which helps the heart toggle between a 'regular maintenance mode' for day-to-day ...

Cardiac hypertrophy is a main contributor to heart failure, where therapeutic options are limited. Increasing evidence exists regarding up-regulation of histone lysine-specific demethylase 4A (KDM4A) ...

A new study details how a protein previously associated with regulating metabolism in the liver also plays a part in maintaining a healthy heart by ensuring that the heart wall is neither too thick ...

Left ventricular hypertrophy (LVH) is when the heart’s main pumping chamber, the left ventricle, becomes thicker and less able to pump blood efficiently. It usually develops because of another heart ...