To search mammalian cells for additional MLH1 interacting proteins, we probed mammalian nuclear extracts with the MLH1–PMS2 interaction domain in a far-western assay and identified a novel 160-kD ...
Reconstitution of the activation of the MLH1–MLH3 endonuclease shows how crossovers are formed during meiosis. When DNA breaks, cells use the homologous recombination pathway to accurately repair the ...
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