Long-read RNA sequencing (RNA-seq) technologies have revolutionized transcriptomic research by enabling the sequencing of full-length RNA molecules, thus providing a more accurate characterization of ...

A third of disease-causing variants are estimated to disrupt mRNA splicing [1, 2]. Splice-affecting variants are often missed and are under-ascertained in clinical variant databases, as these are not ...

Here, Aaron Wenger, Principal Scientist – Bioinformatics at PacBio (CA, USA), explores how advances in accuracy, throughput and cost are making long-read sequencing more accessible at scale. Advances ...

Researchers at the University of California San Diego have identified new genetic variants associated with autism spectrum disorder (ASD) by using long-read whole genome sequencing (LR-WGS), an ...

A new test provides a much more complete picture of DNA than current standard diagnostics and leads to a diagnosis more often ...

Long-read sequencing is transforming the landscape of genomic research, offering exceptional resolution and accuracy in the analysis of complex genetic structures. From research in genetic analysis to ...

The single-cell genomics industry does not stop advancing, with a steady stream of new companies, kits, acquisitions, and more. One new company, ArgenTag, was founded in Argentina during the COVID-19 ...

Genomic DNA is organized into chromatin via nucleosomes, regulating its accessibility for critical biological processes such as transcription, replication, and epigenetic modification. The dynamic ...

In just a few decades, DNA sequencing technologies evolved from slow, manual processes to rapid, automated ones, making ...

Now supporting both Illumina short-read and Oxford Nanopore long-read sequencing platforms, the NGD200 is the industry's first to enable WGS-based hospital transmission detection. CAMBRIDGE, MA / ACCE ...