Intermediate filaments (IFs) are critical parts of the structure of cells. They are essential for both normal tissue structure and function. Enabling cells to withstand the stretch and pressure on the ...

Providing structural support and protection against such conditions as blistering, cataracts and dementia, intermediate filament proteins (IFs) reside in every cell in the human body. In insects, ...

Living cells are constantly exposed to a wide variety of mechanical stresses: heart and lungs must withstand expansion and contraction; our skin must be resistant to tearing whilst retaining ...

Numerous species of prokaryotic and eukaryotic origin are predicted to encode coiled-coil intermediate filament (IF) or IF-like proteins 1,2,3,4. However, the first IF to be studied was of metazoan ...

During the development of multicellular organisms, epithelial cells adhere to each other, followed by the formation of various types of cellular asymmetry such as apico-basal polarity and planar cell ...

Biologists have found a unique version of a filament-forming protein in human cells that insects lack. Providing structural support and protection against such conditions as blistering, cataracts and ...