Antibodies are a critical feature of the human adaptive immune response. New immunotherapies require the production of selective and non-autoimmunogenic antibodies. These engineered antibodies can ...

Trastuzumab is a common treatment for various HER2-positive cancers. It is an antibody that specifically binds to HER2, a problematic protein over-expressed on cancer cells that signals for nonstop ...

"Without any additional adjustments to the proposed designs, the humanized antibodies functioned just as effectively as the mouse's original." Tests of four other antibodies, all designed with CUMAb, ...

A breakthrough for biomedical research promises new insight into immunotherapy development and disease modeling. Scientists at The University of Texas Health Science Center at San Antonio have created ...

Creative Diagnostics launches Humanized Control Antibodies to support the development of diagnostic assays for infectious diseases and quality control. NEW YORK, NY ...

Antibody humanization involves modifying antibodies from non-human sources, such as mice, to decrease their immunogenicity in human applications. While mouse monoclonal antibodies are specific, they ...

Real-world adoption and sequencing of CLDN18.2, PD-L1, and HER2 testing in advanced gastric and gastroesophageal junction adenocarcinoma. A phase 1 study of SHR-3821, an ADCC-enhanced CLDN18.2/4-1BB ...

A prospective, open-label, single-arm phase II clinical study of inetetamab in combination with pyrotinib and albumin-bound paclitaxel for the neoadjuvant treatment of patients with HER2+ early and ...