Biologists are very interested in how proteins, lipids and other compounds are organized and interact in systems. Very few organizational details can be gained by using standard transmission-based ...

Light microscopy is a key tool that scientists use to image cells, organelles, subcellular structures, and molecules such as proteins and nucleic acids. Because visible light leaves biological ...

In a cramped, windowless room on the University of California, Berkeley, campus, two bespoke microscopes—each a Swiss Army ...

Deblurring by pixel reassignment remaps raw fluorescent microscopy images to sharpen images via pixel reassignment. Credit: Zhao and Mertz, doi 10.1117/1.AP.5.6.066004. Obtaining high-resolution ...

The quality of the data obtained from fluorescence imaging studies depends on the system of components used to acquire, analyze, and process the fluorescent images. As an alternative to building a ...

Overcoming the resolution limit in a light microscope of around half a wavelength of light (about 250 nanometers) is one of the most significant developments in optics. Due to the wave nature of light ...

Using a tiny, spherical glass lens sandwiched between two brass plates, the 17th-century Dutch microscopist Antonie van Leeuwenhoek was the first to officially describe red blood cells and sperm cells ...

In a study published in ACS Nano, researchers from National Taiwan University report a new expansion microscopy strategy ...

For the first time, a team of researchers at Stanford University and UC San Diego’s Scripps Institution of Oceanography has uncovered a direct genetic link between fluorescence and color in sea ...