Signaling pathways, for all their elegance, serve but one purpose: to convert extracellular signals into intracellular changes. Whether it's insulin or isoleucine, antigen or adrenaline, the end ...
Kinases catalyze the transfer of the γ-phosphate from adenosine 5´-triphosphate (ATP) to proteins, lipids, sugars, or other acceptors. This process, termed phosphorylation, forms the cornerstone of ...