Enzymes help with specific functions that are vital to the operation and overall health of the human body. They help speed up chemical reactions and are essential for respiration, digestion, muscle ...

Chemical structure for thiamine pyrophosphate and protein structure of transketolase. Thiamine pyrophosphate cofactor in yellow and xylulose 5-phosphate substrate in black. Credit: Thomas ...

Life has evolved over billions of years, adapting to the changing environment. Similarly, enzymes—proteins that speed up biochemical reactions (catalysis) in cells—have adapted to the habitats of ...

A new artificial intelligence tool can predict the functions of enzymes based on their amino acid sequences, even when the enzymes are unstudied or poorly understood. The researchers said the AI tool, ...

Researchers at the Department of Cell and Molecular Biology, Karolinska Institutet have captured the first detailed molecular snapshots of human polynucleotide phosphorylase (hPNPase) in action, ...

Annotations of enzyme function provide critical starting points for generating and testing biological hypotheses, but the quality of functional annotations is hindered by uncertain assignments for ...

CHAMPAIGN, Ill. — A new artificial intelligence tool can predict the functions of enzymes based on their amino acid sequences, even when the enzymes are unstudied or poorly understood. The researchers ...