The enzyme glutamate decarboxylase (GAD) produces the neurotransmitter GABA, using pyridoxal-5’-phosphate (PLP). GAD exists as two isoforms, GAD65 and GAD67. Only GAD65 acts as a major autoantigen, ...

Advances in structural biology have allowed scientists to determine molecular structures with atomic-level detail, sometimes yielding static snapshots that do not reflect the dynamism of proteins.

On-demand instant delivery has increasingly become an integral component of urban logistics systems. Yet, the dynamic mobility pattern of the vast rider fleet introduces significant sustainability ...

Scientists have for the first time looked deep into the protein structure that may determine our vision - and discovered that it is much more dynamic than previously thought. RBP3 not only changes its ...

An international collaborative research team has discovered that G-quadraplex DNA (G4-DNA) accumulates in neurons and dynamically controls the activation and repression of genes underlying long-term ...

In Greek mythology, Proteus, son of Poseidon and prophetic shepherd of sea-beasts, could foretell the future. The elusive sea god was difficult to capture as he assumed many forms—a lion, a serpent, ...

Discover how daily household structure can influence child custody disputes, including routines, caregiving responsibilities, ...