image: A team at the Technical University of Munich (TUM) has induced stem cells to emulate the development of the human heart. The result is a sort of “mini-heart” known as an organoid. It will ...
Using a combination for spatial, single-cell transcriptomics and imaging data from 36 hearts, scientists from the KTH Royal Institute of Technology and their collaborators have come up with what they ...
Heart disease kills 18 million people each year, but the development of new therapies faces a bottleneck: no physiological model of the entire human heart exists – so far. A new multi-chamber organoid ...
Scientists just published the most detailed map of the developing human heart to date. The atlas includes 75 types of heart cells, including cell types in the heart's valves and the muscles that fuel ...
A crucial new mechanism that helps explain how the heart’s major blood vessels form during early development – and how disruptions to this process can lead to serious congenital heart defects – has ...
The interventricular septum separates the heart’s two ventricles and plays a vital role in maintaining correct bloodflow. Sometimes a defect can occur or be present from birth. This can increase the ...
How did your heart form? What triggered your first heartbeat? To this day, the mechanisms of human heart development remain elusive. Researchers know the heart is the first organ to fully function in ...
Infants born with Down syndrome, the genetic condition caused by an extra copy of chromosome 21, or trisomy 21, are highly predisposed to congenital heart defects. It is estimated that nearly half of ...