Scientists have spent decades trying to get medicine across the blood-brain barrier. Two treatments for a rare genetic disorder have already made it through. Now an experimental Alzheimer’s drug is ...

A new mouse study shows the liver-derived hormone FGF21 crosses the blood-brain barrier through a saturable, efflux-limited ...

A CRISPR-engineered rat carrying a truncating Cwh43 allele developed ventricular enlargement, impaired rotarod performance ...

A new Northwestern Medicine study has uncovered key molecular design principles that could help supramolecular therapeutics cross the blood-brain barrier, a major challenge for this novel approach to ...

London's ExCeL center opened AAIC 2026 this morning with the most consequential claim the Alzheimer's field has heard in years: the blood-brain barrier — the endothelial wall that has blocked every ...

Researchers at the National University of Singapore have reported crossing the blood–brain barrier with help from a modified Lactobacillus plantarum. By delivering an appetite-regulating hormone ...

Can you tell me about your work at Sunnybrook and what you’re focusing on now? My background is in brain plasticity and regeneration. Repairing the brain is a fascinating and challenging task. When Dr ...

Scientists from the University of Liverpool and their global collaborators have highlighted the most effective treatments for neurological diseases by overcoming one of medicine's most difficult ...

Scientists are honing transferrin receptors to whisk bulky, anti-Aβ antibodies throughout the brain without setting off ARIA and anemia. By halving the effector function of their antibody transport ...

Denali is advancing multiple investigational therapies designed to cross blood-brain barrier for Alzheimer’s disease, including DNL628 (OTV:MAPT) targeting tau and DNL921 (ATV:Abeta) targeting amyloid ...