Roughly one million people die of untreated kidney failure, worldwide, each year. Despite the major personal and economic burden, only a few new approaches have been deployed to treat or cure kidney ...

Inflammasomes are intracellular multiprotein complexes that detect danger signals and orchestrate innate immune responses by activating caspase-1 and driving the maturation of interleukin-1β and ...

Acute kidney injury (AKI) is a severe renal disorder affecting approximately 10%–15% of hospitalized patients and up to 50% in intensive care units (ICUs). Its pathogenesis involves complex ...

University of Texas at Dallas scientists have discovered a previously unknown "housekeeping" process in kidney cells that ejects unwanted content, resulting in cells that rejuvenate themselves and ...