A hallmark of Parkinson's disease is the buildup of Lewy bodies—misfolded clumps of the protein known as alpha-synuclein.

A new breakthrough study led by researchers at the University of Minnesota Twin Cities could explain why patients with the ...

Believed to be caused by a mix of genetic and environmental factors, Parkinson’s disease is a chronic, progressive disease that affects the central nervous system, particularly the motor system, ...

A new proof-of-concept method reliably engineered a hotspot mutation of SF3B1, a gene-splicing gene, into diverse cancer cell lines, outperforming other contemporary editing approaches. Oncogenesis ...

A new study suggests a gene mutation could have a protective effect against Alzheimer's. The research looked specifically at blood stem cells, which live in the bone marrow and make different types of ...

Cancer cells carry thousands of mutations, but not all mutations are created equal. Some make tumors highly visible to the ...

The traditional view of human genetics is that we are born with a genome that provides a predictive model of our risks of developing different diseases. With a few exceptions, such as cancer, genetic ...

A study published in Cell Stem Cell reveals that some mutations in blood stem cells might help protect against late-onset Alzheimer's disease. A team led by researchers at Baylor College of Medicine ...

UCSF Benioff Children’s Hospital Oakland is enrolling patients in an innovative clinical trial that seeks to cure sickle cell disease. The trial is the first in the U.S. to apply non-viral CRISPR-Cas9 ...

New study by Hebrew University reveals that a significant proportion (over one fifth) of human pluripotent stem cell samples that can be used in regenerative medicine possess cancer-related mutations, ...