Rearranging the parts of a molecule is like rearranging the contents of a tightly packed suitcase: You must go through a number of steps, taking objects in and out to get the configuration you want. A ...

Chemoselective synthesis of carbonyl compounds encompasses a suite of strategies that target the formation or modification of aldehydes and ketones in the presence of other reactive functionalities.

Being able to shuffle functional groups on a molecule is something organic chemists would love to do, but it is not straightforward to do in the lab. A new synthesis designed by Guangbin Dong and ...

Scientists at Scripps Research have used rapid alternating current (AC) to selectively reduce carbonyl groups (J. Am. Chem. Soc. 2021, DOI: 10.1021/jacs.1c06572). The technique avoids side reactions ...