Northwestern Medicine scientists have discovered how calcium signaling channels in microglia—the primary immune cells of the brain—regulate neuroinflammation and promote the development of behaviors ...

Combining microscopy, scanning, and deep learning enables more precise imaging of functional dynamics in neural networks of human cortical organoids.

Researchers have developed a novel method for simultaneously recording action potentials (APs)—temporary changes in electrical potential when cells become excited—and calcium transients—calcium ...

Calcium (Ca 2+) drives many cellular functions, though the way it controls quality of proteins in the endoplasmic reticulum (ER), a cellular organelle that synthesizes and transports proteins, is ...

Deep inside a small, windowless room at the University of California, Berkeley, two microscopes are quietly capturing some of ...

Scientists have developed a new imaging technique that uses a novel contrast mechanism in bioimaging to merge the strengths of two powerful microscopy methods, allowing researchers to see both the ...

Lipids in cell membranes regulate the activity of a cancer-linked protein, cell biologists at RIKEN have discovered. This finding, published in the journal eLife, could pave the way for novel ...

Cell surface receptors, such as the G-protein coupled receptor (GPCR) and receptor tyrosine kinase (RTK), play central roles signalling pathways. Due to their central role in regulating a wide range ...

Nearly 100 years ago, a seemingly simple discovery revolutionized the microscope. The introduction of phase contrast, which ...