Changing an organism’s genome is a profound act, and the tools you use to make the changes don’t alleviate the need for responsible regulation. Unlike “traditional” genetically modified organisms (GMO ...

Charles Gersbach and his colleagues are pursuing promising CRISPR technologies focused on controlling gene activity rather ...

A new kind of CRISPR that destroys cells rather than gene editing them has shown potential for killing sick cells while leaving healthy cells untouched. The technology has largely been tested in cells ...

With the power to rewrite the genetic code underlying countless diseases, CRISPR holds immense promise to revolutionize medicine. But until scientists can deliver its gene-editing machinery safely and ...

CRISPR functions as a programmable genetic memory system derived from bacterial immune defenses against viral infections. Guide RNA allows for rapid multiplexed targeting compared to older ...

Genetic engineering is moving from the lab bench into clinics, farms, and even family planning decisions, promising to change how we prevent disease, age, and define human potential. The same tools ...

The ethics of using safe gene therapies to improve the health and cognition of Down syndrome children and adults.

The U.S. Food and Drug Administration (FDA) on Wednesday initiated an immediate review of clinical trials that involved sending Americans’ living cells to China and other foreign adversaries for ...

Almost 100 years ago, Carrie Buck was raped, labeled an “imbecile,” and sterilized by order of the state — all in the name of genetic progress. Today, we no longer use that word, but the dream of ...

The modification of the genetic makeup of cells. Genetic engineering modifies the DNA in cells to alter their behavior. In 1953, the discovery of the DNA double helix, technically deoxyribonucleic ...