We used maternal immunoglobulin M (IgM), immunoglobulin G (IgG) avidity index (AI) and fetal ultrasonography (US) to effectively detect a congenital cytomegalovirus-infected fetus that would suffer ...

Human cytomegalovirus (CMV) is a common virus found worldwide. When CMV infects fetuses, it can cause serious complications such as hearing difficulties and mental retardation in affected infants. A ...

Classically, detection of IgG antibodies to CMV is diagnostic of past infection and synonymous with the term "seropositivity". Transplant physicians have used this term to predict risk for the ...

Immune substance in the serum portion of the blood that helps fight off and control the infection or disease. There are at least two types of antibodies, IgG and IgM, produced in response to a CMV ...

Congenital cytomegalovirus (CMV) infection can cause serious complications such as hearing difficulties and mental retardation in affected infants. A Japanese research team has discovered a new method ...

Acute cytomegalovirus infection can occur in older adults who are not obviously immunocompromised and should be considered in the differential diagnosis of patients with fever of unknown origin.

I think it would be a bad idea to move forward with donation. I would confirm the serologic test (IgM) with a DNA test (polymerase chain reaction, PCR), which is much more sensitive. If the PCR is ...

In this phase 2, placebo-controlled, randomized, double-blind trial, we evaluated a vaccine consisting of recombinant CMV envelope glycoprotein B with MF59 adjuvant, as compared with placebo. Three ...

Herpes virus infection leads to severe and fatal disease in individuals with suppressed immunity. In patients with inflammatory bowel disease (IBD), particularly those with ulcerative colitis (UC), ...