B cells are a crucial component of immunity, but their function, especially antibody secretion, has largely been studied in the context of secondary lymphoid organs (SLOs) and systemic immune ...

Immune responses and self-tolerance are critical in maintaining systemic and tissue homeostasis. Autoimmune disease results from uncontrolled immune responses against self-antigens, whereas cancer ...

B cells are white blood cells that form a core part of the body's adaptive immune system, enabling it to recognize specific infections, remember them, and mount a targeted response by producing ...

A new study tracking thousands of B cells across more than 100 germinal centers in mice reveals how the system consistently produces highly effective antibodies. The findings overturn longstanding ...

A multinational collaboration co-led by the Garvan Institute of Medical Research has uncovered a potential explanation for why some cancer patients receiving a type of immunotherapy called checkpoint ...

Antibody-mediated rejection (ABMR) remains the leading immunological cause of kidney allograft loss, yet its humoral origins are incompletely understood.