A high-yield, one-pot, scalable reaction facilitates the production of biologically relevant amide compounds using less reactive nitrogen-containing heterocyclic compounds and carboxylic acid without ...
In a chemistry version of whipping up a delicious dinner from pantry staples, researchers in Korea have found a recipe for ...
In proteins, amino acids are held together by amide bonds. These bonds are long-lived and are robust against changes in temperature, acidity or alkalinity. Certain medicines make use of reactions ...
In proteins, amino acids are held together by amide bonds. These bonds are long-lived and are robust against changes in temperature, acidity, or alkalinity. Certain medicines make use of reactions ...
A pair of copper catalysts can create chiral amides in a new, light-driven process, offering a useful alternative to the standard method for making these staples of medicinal chemistry (Nature 2021, ...
Alpha-substituted fatty amines and nitrogen-containing heterocycles are widely found in numerous bioactive natural products, pharmaceutical molecules, and agrochemicals. A recent analysis of small ...
N-acylation of nitrogen-containing heterocyclic compounds is more efficient using DMAPO and Boc2O rather than conventional methods, even with less reactive N-heterocyclic compounds. The reaction ...
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