A man who drove drunk and collided with another vehicle on state Route 163 near Kearny Mesa, killing four men in the other ...

Here are some of the best things to do this week in San Diego, from Monday, June 30 to Friday, July 4. Check back Wednesday ...

Between 1983 and 1992, the Blood Sisters hosted 12 blood drives, demonstrating sustained commitment for nearly a decade.

The San Diego Padres (45-38) visit the Philadelphia Phillies (49-35) Monday, opening a 3-game series. First pitch from ...

A Frozen Zoo is an extensive collection of living cell lines preserved for valuable conservation, research, and future use.

A historic Navy building at San Diego’s Liberty Station is reborn as The Joan, a $43.5 million performing arts center and new ...

UC San Diego scientists are testing a new potential cancer treatment in space. Why it matters: The NASA-funded mission will ...

A new wildfire was reported today at 11:44 a.m. in San Diego County, California. Jamul Fire has been burning on private land ...

Four-star class of 2026 point guard Isaiah Rogers of Centennial High School in Corona has been offered a scholarship by San ...

Zack Wheeler struck out 10 in eight innings, Nick Castellanos homered and the Philadelphia Phillies won in Bryce Harper's ...

San Diego Comic-Con runs from July 24-27, and Predator: Badlands hits theaters on November 7. While we wait for more info ...

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