Kelsey Gramme reveals his sister Karen's chilling final moments after she was stabbed 42 times. She was brutally raped and murdered in Colorado in 1975.

Kelsey Grammer opened up on grief and addiction in a recent interview ahead of the release of his upcoming book "Karen: A Brother Remembers."

In 1975, then-20-year-old actor Kelsey Grammer was home with his family when he received the devastating news that the body of a Jane Doe had been discovered in Colorado Springs, Colorado, and that she was believed to be his younger sister,