The Rams have their work cut out for them in Week 3 but they have a chance to upset the 49ers if they win these 5 matchups

Just as the San Francisco 49ers won’t miss seeing Aaron Donald lining up for the Los Angeles Rams on Sunday, Sean McVay won’t miss game planning against Christian McCaffrey and Deebo Samuel. Both 49ers stars are out with injuries for this weekend’s game at SoFi Stadium,

The San Francisco 49ers have played games without Deebo Samuel Sr. in the last year and a half. And they’ve played games without Christian McCaffrey in the last year and a half. But they’ve never played a game in that span without either Samuel or McCaffrey,

It appears the San Francisco 49ers are quickly seeing some of the adversity generated when a wide receiver misses all of training camp. Wide receiver Brandon Aiyuk and quarterback Brock Purdy haven't been able to get on the same page in the 49ers' first two games.

Brandon Aiyuk’s stat line was not impressive against the Minnesota Vikings, but the 49ers wide receiver said he could see noticeable improvements from the 2024 NFL season opener. “I was happy watching tape this week,