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WEBAdaptimmune’s Afami-cel is the first FDA-approved T-cell receptor therapy for synovial sarcoma. by Amy Boyle and 1 others. September 25, 2024. Afami-cel (Tecelra) is the first genetically engineered T-cell receptor therapy for synovial sarcoma Afami-cel demonstrated an overall response rate of 39% in synovial sarcoma patients.
Infusion with a monoclonal antibody decreases migraine frequency
WEBSep 30, 2024 · 1. In this randomized controlled trial, in patients diagnosed with migraine, it was found that administration of a monoclonal antibody against pituitary adenylate cyclase-activating polypeptide (PACAP), Lu AG09222, was associated with a reduction in migraines frequency. 2. The Lu AG09222 group experienced a higher incidence of adverse events compared to the placebo group, though no
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Landmark Trials & Summaries: The Classics in Medicine - 2 Minute …
WEB3800. 1.It was found that adverse events occurred in 3.7% of hospitalizations 2.Approximately 27.6% of adverse events occurring in hospital were attributed to negligence. The OHTS trial: Topical ocular hypotensive medication reduces risk of open-angle glaucoma.
The Ultimate Guide to Achieving a Competitive MCAT Score for …
WEBNov 28, 2023 · Welcome to the ultimate guide that will help you achieve a competitive MCAT score for your medical school admissions. The MCAT (Medical College Admission Test) is a comprehensive examination that plays a crucial role in the medical school application process.
The Lee index: Risk of perioperative cardiac events [Classics Series ...
WEBSep 27, 2014 · The Lee index is a prospectively validated model that predicts the risk of a cardiac event in patients undergoing noncardiac surgery. 2. The six independent predictors are as follows: 1) high-risk surgery, 2) history of ischemic heart disease, 3) history of congestive heart failure, 4) history of cerebrovascular disease, 5) preoperative ...
Patient Basics: Epiglottitis - 2 Minute Medicine
WEBNov 30, 2014 · Epiglottitis is a rare, but potentially life-threatening infection. It causes sudden swelling of the epiglottis, which often worsens rapidly, sometimes within hours. Without timely treatment, the epiglottis can become so large that it blocks the windpipe, making it hard to breathe. This can cause death. Epiglottitis can occur at any age.
Biomarkers may help guide antibiotic stewardship in community …
WEBAug 26, 2024 · 1. Using either procalcitonin or c-reactive protein as a biomarker to guide antibiotic treatment in patients with community-acquired pneumonia reduces the length of treatment course with no effect to time to reach stability or new antibiotic prescriptions Evidence Rating Level: 1 (Excellent) 20-50% of the 3.3 million people who develop community-acquired pneumonia (CAP) need to
The ARMA trial: Lower tidal volume ventilation in ALI/ARDS …
WEB1. The trial was terminated early when the data demonstrated that lower tidal volume ventilator settings in ALI/ARDS patients led to a significant decrease in in-hospital mortality. 2. Low tidal volume ventilation also led to an increase in ventilator-free days and a decrease in the number of days with systemic organ failure. There was no.
Mediterranean diet effects on vascular health and serum levels of ...
WEBAug 15, 2024 · 1. The effect of the Mediterranean Diet on cardiovascular health can be partially explained by improved vascular health, lowered total cholesterol and LDL, lowered ceramides, and reduced serum inflammatory adipokines. Evidence Rating Level: 1 (Excellent) Study Rundown: The Mediterranean Diet has been previously shown to improve cardiovascular outcomes in patients. This is proposed to be